Table 5 Antibacterial activity of all major part extracts in aqueous and organic solvent of C. papaya against gram positive and gram negative bacterial strains (mean ± SE; n = 3)

Pulp

S.aureus

7.8 ± 0.2^b

10.5 ± 0.5^ab

9.0 ± 0.5^b

11.9 ± 1.3^a

9.0 ± 0.5^a

13.0 ± 0.0^b

17.8 ± 0.0^a

21.5 ± 0.8

B. cereus

6.8 ± 0.5^c

10.1 ± 0.5^ab

10.0 ± 0.2^a

12.2 ± 0.6^a

8.7 ± 0.8^a

12.9 ± 0.8^b

15.9 ± 0.8^a

18.6 ± 0.6

E. coli

9.3 ± 0.1^a

11.2 ± 0.1^a

9.0 ± 0.1^b

10.1 ± 0.0^a

9.2 ± 0.0^a

11.5 ± 0.1^b

16.9 ± 0.0^a

22.3 ± 1.1

P. multocida

7.9 ± 0.3^b

9.7 ± 0.7^b

10.0 ± 0.9^a

11.5 ± 1.2^a

7.9 ± 2.4^a

14.8 ± 1.7^a

18.1 ± 1.2^a

21.2 ± 1.2

LSD 5 %

0.59***

0.94*

1.01*

1.76 ^ns

2.41 ^ns

1.80*

1.40*

Leaves

S.aureus

6.7 ± 0.2^a

6.7 ± 0.2^b

5.9 ± 0.4^c

9.2 ± 0.3^a

7.3 ± 0.1^c

9.2 ± 0.2^d

16.2 ± 0.3^a

21.5 ± 0.8

B. cereus

5.7 ± 0.2^b

5.2 ± 0.4^d

5.9 ± 0.4^c

7.2 ± 0.3^c

9.0 ± 0.2^b

11.0 ± 0.1^b

14.5 ± 0.2^c

18.6 ± 0.6

E. coli

6.9 ± 0.0^a

6.3 ± 0.0^c

7.5 ± 0.1^b

8.2 ± 0.2^b

9.0 ± 0.1^b

10.0 ± 0.4^c

14.3 ± 0.1^c

22.3 ± 1.1

P. multocida

5.6 ± 0.9^b

7.2 ± 0.2^a

8.1 ± 0.1^a

9.2 ± 0.2^a

9.2 ± 0.1^a

13.2 ± 0.5^a

15.3 ± 0.3^a

21.2 ± 1.2

LSD 5 %

0.97*

0.31***

0.60***

0.45***

0.25***

0.62***

0.40***

Seed

S.aureus

5.5 ± 0.2^b

4.6 ± 0.0^c

9.0 ± 0.2^b

9.7 ± 0.4^b

8.7 ± 0.3^c

9.9 ± 0.4^b

14.0 ± 0.3^a

21.5 ± 0.8

B. cereus

6.1 ± 0.3^a

7.3 ± 0.4^a

9.5 ± 0.1^a

9.1 ± 0.1^c

10.1 ± 0.0^a

11.3 ± 0.0^a

11.7 ± 0.2^b

18.6 ± 0.6

E. coli

5.0 ± 0.1^c

6.8 ± 0.0^b

8.7 ± 0.2^c

10.5 ± 0.0^a

9.6 ± 0.1^b

10.9 ± 0.3^a

14.0 ± 0.1^a

22.3 ± 1.1

P. multocida

6.3 ± 0.2^a

6.5 ± 0.3^b

8.4 ± 0.2^c

9.0 ± 0.1^c

10.4 ± 0.3^a

10.1 ± 0.1^b

13.8 ± 0.1^a

21.2 ± 1.2

LSD 5 %

0.36***

0.47***

0.35***

0.38***

0.38***

0.49***

0.31***

Roots

S. aureus

4.0 ± 0.1^b

7.0 ± 1.0^a

8.0 ± 0.3^a

8.3 ± 0.3^b

7.2 ± 0.4^a

10.2 ± 0.4^a

10.5 ± 1.0^a

21.5 ± 0.8

B. cereus

3.8 ± 0.9^b

7.0 ± 0.9^a

7.6 ± 0.6^a

8.2 ± 0.6^b

8.0 ± 0.4^a

9.3 ± 0.2^a

9.5 ± 0.0^a

18.6 ± 0.6

E. coli

5.8 ± 0.0^a

8.6 ± 0.1^a

9.1 ± 0.0^a

8.0 ± 0.4^b

8.5 ± 0.4^a

9.9 ± 0.2^a

11.0 ± 0.0^a

22.3 ± 1.1

P. multocida

5.5 ± 0.1^a

8.1 ± 0.1^a

8.7 ± 1.0^a

9.0 ± 0.0^a

10.0 ± 1.9^a

10.2 ± 1.2^a

11.7 ± 1.0^a

21.2 ± 1.2

LSD 5 %

0.86**

1.24*

1.11 ^ns

0.61*

1.89*

1.26 ^ns

1.31*

Peels

S. aureus

5.4 ± 0.1^a

5.6 ± 0.0^b

6.4 ± 0.1^d

7.0 ± 0.4^a

7.7 ± 0.4^a

8.1 ± 0.3^c

12.5 ± 0.3^c

21.5 ± 0.8

B. cereus

5.3 ± 1.5^a

5.6 ± 0.2^b

6.7 ± 0.0^c

7.4 ± 0.1^ab

7.9 ± 0.9^a

8.12 ± 0.1^c

14.8 ± 0.2^a

18.6 ± 0.6

E. coli

6.5 ± 0.0^a

5.8 ± 0.1^ab

7.3 ± 0.1^a

8.0 ± 0.4^a

8.6 ± 0.2^a

9.1 ± 0.0^a

13.6 ± 0.3^b

22.3 ± 1.1

P. multocida

5.9 ± 1.3^a

6.0 ± 0.1^a

7.0 ± 0.2^b

7.8 ± 0.3^a

8.0 ± 0.0^a

8.8 ± 0.1^b

12.5 ± 1.2^c

21.2 ± 1.2

LSD 5 %

1.87 ^ns

0.26*

0.18***

0.62*

0.96 ^ns

0.13***

0.83*

Bark

S.aureus

6.9 ± 0.0^a

7.1 ± 1.2^a

7.5 ± 1.2^a

8.0 ± 1.9^a

8.0 ± 1.1^a

8.9 ± 1.3^a

10.9 ± 1.1^a

21.5 ± 0.8

B. cereus

6.1 ± 0.0^b

7.3 ± 1.0^a

7.4 ± 1.5^a

8.5 ± 0.3^a

8.0 ± 0.1^a

9.1 ± 1.5^a

10.5 ± 1.6^a

18.6 ± 0.6

E. coli

5.9 ± 0.1^b

7.8 ± 0.0^a

8.0 ± 0.1^a

8.9 ± 0.2^a

9.0 ± 0.0^a

10.5 ± 0.0^a

11.0 ± 0.0^a

22.3 ± 1.1

P. multocida

7.5 ± 0.7^a

7.6 ± 0.3^a

8.0 ± 1.2^a

9.4 ± 1.4^a

8.3 ± 0.7^a

10.0 ± 2.1^a

11.0 ± 1.0^a

21.2 ± 1.2

LSD 5 %

0.66**

1.50 ^ns

2.16 ^ns

2.23 ^ns

1.22 ^ns

2.72 ^ns

2.06 ^ns