Compound | IC50(nM) | |||
---|---|---|---|---|
MDA-MB-231 | MCF-7 | K562 | A549 | |
CA-4 | 6.27 | 10.49 | 5.75 | 428 |
6 | 12.29 | 8.00 | 7.68 | 693 |
7(CA-4E) | 2.30 | 1.32 | <2.50 | 180 |
8a | 7.26 | 8.38 | 14.78 | 486 |
8b | 7.77 | 7.59 | 14.88 | 476 |
9a | 7.94 | 10.04 | 14.90 | 309 |
9b | 6.68 | 11.29 | 8.76 | 330 |
10 | 6.40 | 10.39 | 9.42 | 435 |
11 | 4.39 | 12.46 | 12.28 | 316 |
12 | 7.27 | 7.09 | 8.85 | 265 |
13 | 12.23 | 10.85 | 9.65 | 735 |
14 | 39.60 | 66.09 | 80.84 | >1000 |