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Table 3 Cytotoxic effects of the tested extracts

From: Isolation of anticancer constituents from flos genkwa (Daphne genkwaSieb.et Zucc.) through bioassay-guided procedures

 

Huh 7

A 2058

B 16

231

MCF-7

COLO 205

A 549

AGS

HT-29

 

IC50μg/mL

Crude extract

>500

97

>500

>500

>500

>500

260

>500

>500

Petroleum ether

>500

89

>500

>500

>500

306

>500

217

>500

Dichloromethane

>500

50

98

>500

260

289

>500

>500

50

n-butanol

>500

>500

>500

>500

>500

>500

>500

>500

>500

Water

>500

>500

>500

>500

>500

431

>500

>500

>500

  1. Inhibitory effects of the extracts from the Flos Genkwa on the proliferation of MDA-MB-231, Huh 7, AGS, Colo 205, MCF-7, HT-29, A 549, A 2058 and B 16 cells. Cells were treated with 0–50 μg/mL of extracts for 24 h.