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Table 6 Polycyclic aromatic hydrocarbons reported in STPs and those included in the FDA HPHC established list

From: Polycyclic aromatic hydrocarbons in US and Swedish smokeless tobacco products

 

IARC classification1

FDA HPHC established List [3]

Current study

Stepanov et al. [21]

Stepanov et al. [12]

Acenaphthene

3

 

yes

 

yes

Acenaphthylene

Not listed

 

yes

yes

yes

Anthracene

3

 

yes

yes

yes

Benz[a]anthracene

2B

yes

yes

 

yes

Benz[j]aceanthrylene

2B

yes

   

Benzo[a]pyrene

1

yes

yes

yes

yes

Benzo[e]pyrene

3

 

yes

 

yes

Benzo[b]fluoranthene

2B

yes

yes

yes5

yes2

Benzo[c]phenanthrene

2B

yes

   

Benzo[j]fluoranthene

2B

 

yes

 

yes2

Benzo[k]fluoranthene

2B

yes

yes

yes5

yes

Benzo[ghi]perylene

3

 

yes

 

yes

Chrysene

2B

 

yes

 

yes

1-methylchrysene

3

   

yes4

3-methylchrysene

3

   

yes4

4- & 6-methylchrysene

3

   

yes4

5-methylchrysene

2B

yes

  

yes3,4

Cyclopenta[c,d]pyrene

2A

yes

   

Dibenz[a,h]anthracene

2A

yes

yes

 

yes

Dibenzo[a,e]pyrene

2B

yes

   

Dibenzo[a,h]pyrene

2B

yes

   

Dibenzo[a,i]pyrene

2B

yes

   

Dibenzo[a,l]pyrene

2A

yes

   

Fluoranthene

3

 

yes

yes

yes

Fluorene

3

 

yes

 

yes

Indeno[1,2,3-cd]pyrene

2B

yes

yes

 

yes

Naphthalene

2B

yes

yes

 

yes

1-methylnaphthalene

Not listed

 

yes

  

2-methylnaphthalene

Not listed

 

yes

  

Perylene

3

 

yes

  

Phenanthrene

3

 

yes

yes

yes

Pyrene

3

 

yes

yes

yes

  1. 1IARC class key: Group 1: Carcinogenic to humans, Group 2A: Probably carcinogenic to humans, Group 2B: Possibly carcinogenic to humans, Group 3: Not classifiable as to carcinogenicity to humans.
  2. 2Benzo[b]fluoranthene and benzo[j]fluoranthene were not separated.
  3. 35-methyl chrysene was not detected in any of the samples.
  4. 4methylchrysenes reported as “total methylchrysenes”.
  5. 5Benzo[b]fluoranthene and benzo[k]fluoranthene were not separated.