From: Derivative spectrophotometric analysis of benzophenone (as an impurity) in phenytoin
Parameter | Proposed method | Comparison method(13) | ||
---|---|---|---|---|
First derivative method (1D) | Third derivative method (3D) | Ratio derivative method (1DD) | ||
% Found(a) | 098.18 | 102.35 | 102.03 | 100.56 |
100.41 | 099.84 | 100.50 | 099.89 | |
100.20 | 099.63 | 099.20 | 100.01 | |
100.37 | 100.12 | 099.66 | ||
099.81 | 099.20 | 100.15 | ||
099.96 | 100.51 | 100.11 | ||
Mean () ± S.D. | 099.82 ± 0.83 | 100.27 ± 1.10 | 100.27 ± 0.97 | 100.15 ± 0.36 |
T | 0.64 | 0.18 | 0.20 | |
F | 5.48 | 9.61 | 7.37 |