From: Simple isatin derivatives as free radical scavengers: Synthesis, biological evaluation and structure-activity relationship
Compound
R
Time (h)
Yield (%)
1
H
_
2
CH3
4
87
3
C2H5
12
89
(CH2)2CH3
5
(CH2)3CH3
24
93
6
(CH2)4CH3
90
7
(CH2)5CH3
95
8
CH2CH = CH2
9
CH2C6H5
10
CH2COOC2H5
11
C2H4Cl
79
C2H4Br
83