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  1. Research Article

    Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines

    Curcumin is one of the leading compound extracted from the dry powder of Curcuma longa (Zingiberaceae family), which possess several pharmacological properties. However, in vivo administration exhibited limited a...

    Siti Noor Hajar Zamrus, Muhammad Nadeem Akhtar, Swee Keong Yeap, Ching Kheng Quah, Wan-Sin Loh, Noorjahan Banu Alitheen, Seema Zareen, Saiful Nizam Tajuddin, Yazmin Hussin and Syed Adnan Ali Shah

    Chemistry Central Journal 2018 12:31

    Published on: 19 March 2018

  2. Research Article

    Synthesis, antimicrobial activity, pharmacophore modeling and molecular docking studies of new pyrazole-dimedone hybrid architectures

    Design and synthesis of pyrazole-dimedone derivatives were described by one-pot multicomponent reaction as new antimicrobial agents. These new molecular framework were synthesized in high yields with a broad s...

    Assem Barakat, Abdullah M. Al-Majid, Bander M. Al-Qahtany, M. Ali, Mohamed Teleb, Mohamed H. Al-Agamy, Sehrish Naz and Zaheer Ul-Haq

    Chemistry Central Journal 2018 12:29

    Published on: 14 March 2018

  3. Research article

    The effect of melanin-free extract from Sepia esculenta ink on lipid peroxidation, protein oxidation and water-holding capacity of tilapia fillet during cold storage

    Preservative effect of melanin-free extract of Sepia esculenta ink (MFESI) on Sparus latus fillet has been verified in our previous work. This study aims to further approach the mechanism of MFESI for extending t...

    Zhen-Hua Duan, Hua-Zhong Liu, Ping Luo, Yi-Peng Gu and Yan-Qun Li

    Chemistry Central Journal 2018 12:30

    Published on: 14 March 2018

  4. Research article

    Rice bran nanofiber composites for stabilization of phytase

    This study explores the potential application of rice bran (agro waste) to nano-encapsulate phytase, which is a thermally unstable biologically active enzyme. Rice bran was converted to nanofibers (20–50 nm in...

    Upendra A. Rathnayake, Tharindu Senapathi, Chanaka Sandaruwan, Sanja Gunawardene, Veranja Karunaratne and Nilwala Kottegoda

    Chemistry Central Journal 2018 12:28

    Published on: 14 March 2018

  5. Research article

    Optimized method for determination of 16 FDA polycyclic aromatic hydrocarbons (PAHs) in mainstream cigarette smoke by gas chromatography–mass spectrometry

    A gas chromatography–mass spectrometry (GC–MS) method was validated for the determination of 16 polycyclic aromatic hydrocarbons (PAHs) from the FDA list of 93 harmful or potentially harmful constituents of ma...

    Jana Jeffery, Maria Carradus, Karolina Songin, Michael Pettit, Karl Pettit and Christopher Wright

    Chemistry Central Journal 2018 12:27

    Published on: 13 March 2018

  6. Research Article

    Experimental and theoretical study of donor-π-acceptor compounds based on malononitrile

    A set of different donor-π-acceptor compounds having dicyanovinyl as the acceptor and aryl moieties as donors were synthesized by Knoevenagel condensation. The UV–visible absorption and fluorescence spectra we...

    Mohie E. M. Zayed, Reda M. El-Shishtawy, Shaaban A. Elroby, Khalid O. Al-Footy and Zahra M. Al-amshany

    Chemistry Central Journal 2018 12:26

    Published on: 9 March 2018

  7. Research Article

    Synthesis and characterization of novel iminobenzoates with terminal pyrazine moieties

    Apart from its numerous biological activities like antidiabetic, anti-inflammatory, antimicrobial, pyrazine moiety plays an important role in luminescent materials. Its role in luminescent materials is due to ...

    Mushtaq Ahmad, Zahida Perveen, Adailton J. Bortoluzzi, Shahid Hameed, Muhammad R. Shah, Muhammad Tariq, Ghias ud Din, Muhammad T. Jan, Muhammad Siddique and Muhammad Anwar

    Chemistry Central Journal 2018 12:25

    Published on: 8 March 2018

  8. Research Article

    Thermogravimetric analysis, kinetic study, and pyrolysis–GC/MS analysis of 1,1ʹ-azobis-1,2,3-triazole and 4,4ʹ-azobis-1,2,4-triazole

    In general, the greater the number of directly linked nitrogen atoms in a molecule, the better its energetic performance, while the stability will be accordingly lower. But 1,1ʹ-azobis-1,2,3-triazole (1) and 4,4ʹ...

    Chenhui Jia, Yuchuan Li, Shujuan Zhang, Teng Fei and Siping Pang

    Chemistry Central Journal 2018 12:22

    Published on: 1 March 2018

  9. Research

    Synthesis, structural determination and antimicrobial evaluation of two novel CoII and ZnII halogenometallates as efficient catalysts for the acetalization reaction of aldehydes

    Complexes of imidazole derivatives with transition metal ions have attracted much attention because of their biological and pharmacological activities, such as antimicrobial, antifungal, antiallergic, antitumo...

    Assila Maatar Ben Salah, Lilia Belghith Fendri, Thierry Bataille, Raquel P. Herrera and Houcine Naïli

    Chemistry Central Journal 2018 12:24

    Published on: 1 March 2018

  10. Research Article

    Simultaneous determination of myricetrin, quercitrin and afzelin in leaves of Cercis chinensis by a fast and effective method of ionic liquid microextraction coupled with HPLC

    In this study, the contents of myricetrin, quercitrin and afzelin in Cercis chinensis leaves were determined simultaneously by 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM] BF4/70% ethanol microextraction ...

    Mengjun Shi, Nan He, Wenjing Li, Changqin Li and Wenyi Kang

    Chemistry Central Journal 2018 12:23

    Published on: 1 March 2018

  11. Research Article

    Relationship between the binding free energy and PCBs’ migration, persistence, toxicity and bioaccumulation using a combination of the molecular docking method and 3D-QSAR

    The molecular docking method was used to calculate the binding free energies between biphenyl dioxygenase and 209 polychlorinated biphenyl (PCB) congeners. The relationships between the calculated binding free...

    Xiao-Hui Zhao, Xiao-Lei Wang and Yu Li

    Chemistry Central Journal 2018 12:20

    Published on: 23 February 2018

  12. Research Article

    A new family of azanaphthoquinones for antimicrobial evaluation

    This article presents a complete and detailed study of synthesis, structural characterization, and possible applications of a new family of azanaphthoquinones as antimicrobial agents. A series of (alkoxy)pheny...

    Nilüfer Bayrak

    Chemistry Central Journal 2018 12:21

    Published on: 23 February 2018

  13. Research Article

    Synthesis of multifunctional activated carbon nanocomposite comprising biocompatible flake nano hydroxyapatite and natural turmeric extract for the removal of bacteria and lead ions from aqueous solution

    Clean water, which is free from pathogens and toxic chemicals, is vital to human health. The blue planet is encountering remarkable challenges in meeting the ever-increasing demands of clean water. The intenti...

    H. D. A. Chathumal Jayaweera, Induni Siriwardane, K. M. Nalin de Silva and Rohini M. de Silva

    Chemistry Central Journal 2018 12:18

    Published on: 21 February 2018

  14. Research Article

    Phytochemical constituents, antioxidant activity, and antiproliferative properties of black, red, and brown rice bran

    In the recent years, the health benefits of the pigmented rice varieties have reported due to the presence of bioactive compounds. In this study, the phytochemical constituents (total phenolic, flavonoid and a...

    Ali Ghasemzadeh, Mohamad Taghi Karbalaii, Hawa Z. E. Jaafar and Asmah Rahmat

    Chemistry Central Journal 2018 12:17

    Published on: 17 February 2018

  15. Research Article

    Anti-inflammatory effect of oligostilbenoids from Vitis heyneana in LPS-stimulated RAW 264.7 macrophages via suppressing the NF-κB activation

    Vitis heyneana is widely distributed in the north of Vietnam, it has been used in Vietnamese traditional medicine as an agent for treatment of arthritis, bronchitis, carbuncles and inflammatory conditions, and me...

    Do Thi Ha, Phung Thanh Long, Tran Thi Hien, Dao Trong Tuan, Nguyen Thi Thuy An, Nguyen Minh Khoi, Ha Van Oanh and Tran Manh Hung

    Chemistry Central Journal 2018 12:14

    Published on: 13 February 2018

  16. Research article

    Effect of crosslinking concentration on properties of 3-(trimethoxysilyl) propyl methacrylate/N-vinyl pyrrolidone gels

    The incorporation of two different monomers, having different properties, in the same polymer molecule leads to the formation of new materials with great scientific and commercial importance. The basic require...

    Ameen Hadi Mohammed, Mansor B. Ahmad, Nor Azowa Ibrahim and Norhazlin Zainuddin

    Chemistry Central Journal 2018 12:15

    Published on: 13 February 2018

  17. Commentary

    Better agonist for the opioid receptors

    This commentary highlights the recent work published in journal Nature on the structural based discovery of novel analgesic compounds for opioid receptors with minimal effects. Manglik et al. selectively targe...

    Syed Lal Badshah, Asad Ullah, Salim S. Al-showiman and Yahia Nasser Mabkhot

    Chemistry Central Journal 2018 12:13

    Published on: 8 February 2018

  18. Research Article

    Synthesis, characterization, molecular docking evaluation, antiplatelet and anticoagulant actions of 1,2,4 triazole hydrazone and sulphonamide novel derivatives

    In the present study, a series of new hydrazone and sulfonamide derivatives of 1,2,4-triazole were synthesized. Initially three 4-substituted-5-(2-pyridyl)-1,2,4-triazole-3-thiones ZE-1(a–c) were treated with ...

    Waseem Khalid, Amir Badshah, Arif-ullah Khan, Humaira Nadeem and Sagheer Ahmed

    Chemistry Central Journal 2018 12:11

    Published on: 7 February 2018

  19. Research article

    Assessment and comparison of phytochemical constituents and biological activities of bitter bean (Parkia speciosa Hassk.) collected from different locations in Malaysia

    Parkia speciosa seeds are a common ingredient in Malay cuisine with traditional interest because of its medicinal importance and content of health-promoting phytochemicals. This study evaluated the phytochemical ...

    Ali Ghasemzadeh, Hawa Z. E. Jaafar, Mohamad Fhaizal Mohamad Bukhori, Mohd Hafizad Rahmat and Asmah Rahmat

    Chemistry Central Journal 2018 12:12

    Published on: 7 February 2018

  20. Research article

    Surface thiolation of silicon for antifouling application

    Thiol groups grafted silicon surface was prepared as previously described. 1H,1H,2H,2H-perfluorodecanethiol (PFDT) molecules were then immobilized on such a surface through disulfide bonds formation. To investiga...

    Xiaoning Zhang, Pei Gao, Valerie Hollimon, DaShan Brodus, Arion Johnson and Hongmei Hu

    Chemistry Central Journal 2018 12:10

    Published on: 7 February 2018

  21. Correction

    Correction to: Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

    After publication of the original article [1], the following error was reported in the Results section of the Abstract: “antifungal activity against one yeast i.e. Aspergillus niger” should read: “antifungal acti...

    Parvin Kumar, Kulbir Kadyan, Meenakshi Duhan, Jayant Sindhu, Vineeta Singh and Baljeet Singh Saharan

    Chemistry Central Journal 2018 12:9

    Published on: 6 February 2018

    The original article was published in Chemistry Central Journal 2017 11:115

  22. Research Article

    Notable mixed substrate fermentation by native Kodamaea ohmeri strains isolated from Lagenaria siceraria flowers and ethanol production on paddy straw hydrolysates

    Bioethanol obtained by fermenting cellulosic fraction of biomass holds promise for blending in petroleum. Cellulose hydrolysis yields glucose while hemicellulose hydrolysis predominantly yields xylose. Economi...

    Shalley Sharma, Anju Arora, Pankhuri Sharma, Surender Singh, Lata Nain and Debarati Paul

    Chemistry Central Journal 2018 12:8

    Published on: 5 February 2018

  23. Research article

    Experimental and theoretical studies of Schiff bases as corrosion inhibitors

    Relatively inexpensive, stable Schiff bases, namely 3-((4-hydroxybenzylidene)amino)-2-methylquinazolin-4(3H)-one (BZ3) and 3-((4-(dimethylamino)benzylidene)amino)-2-methylquinazolin-4(3H)-one (BZ4), were employed...

    Dalia M. Jamil, Ahmed K. Al-Okbi, Shaimaa B. Al-Baghdadi, Ahmed A. Al-Amiery, Abdulhadi Kadhim, Tayser Sumer Gaaz, Abdul Amir H. Kadhum and Abu Bakar Mohamad

    Chemistry Central Journal 2018 12:7

    Published on: 5 February 2018

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