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Biological Chemistry

This section publishes peer-reviewed open access articles in all areas of biologically- and medically-related chemistry including biochemistry, chemical biology, biotechnology, biomacromolecules, medicinal chemistry, carbohydrate chemistry, and toxicology.

Note: As of 2018, this section is being re-launched as Chemical Biology. Whilst the Section page is under development, readers can find out more about the scope and editors of this section here.


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  1. Content type: Research Article

    Ricinus communis (castor plant) is a potent medicinal plant, which is commonly used in the treatment of various ailments. The present study was conducted to appraise the cytotoxicity and mutagenicity of R. commun...

    Authors: Mazhar Abbas, Abid Ali, Muhammad Arshad, Asia Atta, Zahed Mehmood, Imtiaz Mahmood Tahir and Munawar Iqbal

    Citation: Chemistry Central Journal 2018 12:3

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  2. Content type: Research article

    This study focused on maximizing the extraction yield of total phenolics and flavonoids from Curcuma Zedoaria leaves as a function of time (80–120 min), temperature (60–80 °C) and ethanol concentration (70–90 v/v...

    Authors: Nur Fauwizah Azahar, Siti Salwa Abd Gani and Nor Fadzillah Mohd Mokhtar

    Citation: Chemistry Central Journal 2017 11:96

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  3. Content type: Review

    The sunflower (Helianthus annuus L.) seed and sprout is a ubiquitous crop with abundant nutrients and biological activities. This review summarizes the nutritional and medical importance currently recognized but ...

    Authors: Shuangshuang Guo, Yan Ge and Kriskamol Na Jom

    Citation: Chemistry Central Journal 2017 11:95

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  4. Content type: Research article

    The crystal structure of a commercially available form of human recombinant (HR) insulin, Insugen (I), used in the treatment of diabetes has been determined to 0.92 Å resolution using low temperature, 100 K, s...

    Authors: David R. Lisgarten, Rex A. Palmer, Carina M. C. Lobley, Claire E. Naylor, Babur Z. Chowdhry, Zakieh I. Al-Kurdi, Adnan A. Badwan, Brendan J. Howlin, Nicholas C. J. Gibbons, José W. Saldanha, John N. Lisgarten and Ajit K. Basak

    Citation: Chemistry Central Journal 2017 11:73

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  5. Content type: Research article

    Developing an efficient lipophilization reaction system for phenolic derivatives could enhance their applications in food processing. Low solubility of phenolic acids reduces the efficiency of phenolic derivat...

    Authors: Somayeh Gholivand, Ola Lasekan, Chin Ping Tan, Faridah Abas and Leong Sze Wei

    Citation: Chemistry Central Journal 2017 11:44

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  6. Content type: Preliminary communication

    Plants contain a myriad of metabolites which exhibit diverse biological activities. However, in-depth analyses of these natural products with current analytical platforms remains an undisputed challenge due to...

    Authors: Keabetswe Masike, Msizi I. Mhlongo, Shonisani P. Mudau, Ofentse Nobela, Efficient N. Ncube, Fidele Tugizimana, Mosotho J. George and Ntakadzeni E. Madala

    Citation: Chemistry Central Journal 2017 11:29

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  7. Content type: Research article

    Litchi (Litchi chinensis Sonn.) is a subtropical fruit with attractive characteristic of white to creamy semitranslucent flesh and red color in pericap, but it was easily subjected to the infection of Peronophyth...

    Authors: Hai Liu, Guoxing Jing, Yueming Jiang, Fuying Luo and Zaifeng Li

    Citation: Chemistry Central Journal 2017 11:14

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  8. Content type: Research Article

    The antibacterial activity of 21 nm TiO2 nanoparticles (NPs) and particles modified with Garcinia zeylanica (G. zeylanica) against Methicillin resistant Staphylococcus aureus was investigated in the presence and ...

    Authors: U. L. N. H. Senarathna, S. S. N. Fernando, T. D. C. P. Gunasekara, M. M. Weerasekera, H. G. S. P. Hewageegana, N. D. H. Arachchi, H. D. Siriwardena and P. M. Jayaweera

    Citation: Chemistry Central Journal 2017 11:7

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  9. Content type: Research article

    Glomerular filtration rate (GFR) is usually determined by estimation of iothalamate (IOT) clearance. We have developed and validated an accurate and robust method for the analysis of IOT in human plasma and ur...

    Authors: Iltaf Shah, James Barker, Declan P. Naughton, Stephen J. Barton and Syed Salman Ashraf

    Citation: Chemistry Central Journal 2016 10:80

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  10. Content type: Research article

    A protein, Tm1631 from the hyperthermophilic organism Thermotoga maritima belongs to a domain of unknown function protein family. It was predicted that Tm1631 binds with the DNA and that the Tm1631–DNA complex is...

    Authors: Mitja Ogrizek, Janez Konc, Urban Bren, Milan Hodošček and Dušanka Janežič

    Citation: Chemistry Central Journal 2016 10:41

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  11. Content type: Research Article

    Phenoxazinone synthase (PHS) is a laccase-like multicopper oxidase originating from Streptomyces with great industrial application potential. In this paper, we prepared the PHS nanogel retaining 82 % of its initi...

    Authors: Honghua Jia, Zhen Gao, Yingying Ma, Chao Zhong, Chunming Wang, Hua Zhou and Ping Wei

    Citation: Chemistry Central Journal 2016 10:34

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  12. Content type: Methodology

    Volatile organic compounds (VOCs) can be intermediates of metabolic pathways and their levels in biological samples may provide a better understanding about diseases in addition to potential methods for diagno...

    Authors: Raphael B. M. Aggio, Arno Mayor, Séamus Coyle, Sophie Reade, Tanzeela Khalid, Norman M. Ratcliffe and Chris S. J. Probert

    Citation: Chemistry Central Journal 2016 10:9

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  13. Content type: Review

    Age-associated neurodegenerative disorders such as Alzheimer’s disease are a major public health challenge, due to the demographic increase in the proportion of older individuals in society. However, the relat...

    Authors: Xi Chen, Jeff W. Barclay, Robert D. Burgoyne and Alan Morgan

    Citation: Chemistry Central Journal 2015 9:65

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  14. Content type: Research article

    Chlorogenic acids (CGAs) are a class of phytochemicals that are formed as esters between different derivatives of cinnamic acid and quinic acid molecules. In plants, accumulation of these compounds has been li...

    Authors: Efficient N Ncube, Msizi I Mhlongo, Lizelle A Piater, Paul A Steenkamp, Ian A Dubery and Ntakadzeni E Madala

    Citation: Chemistry Central Journal 2014 8:66

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  15. Content type: Research article

    Zanthoxylum buesgenii is a shrub used in Sierra Leone as remedy to cure venereal diseases, arthritis, and rheumatism whereas leaves and barks are employed to treat leprosy and to relieve pain. In South West Regio...

    Authors: Louis P Sandjo, Victor Kuete, Rodrigue S Tchangna, Thomas Efferth and Bonaventure T Ngadjui

    Citation: Chemistry Central Journal 2014 8:61

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  16. Content type: Erratum

    This is a correction to the following paper: General peroxidase activity of a parallel G-quadruplex-hemin DNAzyme formed by Pu39WT - a mixed G-quadruplex forming sequence in the Bcl-2 P1 promoter, Bo Liu, Da L...

    Authors: Bo Liu, Hong Shang and Da Li

    Citation: Chemistry Central Journal 2014 8:57

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    The original article was published in Chemistry Central Journal 2014 8:43

  17. Content type: Mini review

    Advances in biomedical science are leading to upsurge synthesis of nanodelivery systems for drug delivery. The systems were characterized by controlled, targeted and sustained drug delivery ability. Humans are...

    Authors: Aminu Umar Kura, Sharida Fakurazi, Mohd Zobir Hussein and Palanisamy Arulselvan

    Citation: Chemistry Central Journal 2014 8:46

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