Analytical Chemistry

This section publishes peer-reviewed open access articles in all areas of analytical chemistry including spectroscopy, crystallography, chromatography, imaging, chemometrics, data processing, and electrochemistry.

Section Editors: Yitao Long, Richard Brereton and Elizabeth Ostler


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  1. Research article

    The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa

    Pressurized hot water extraction (PHWE) technique has recently gain much attention for the extraction of biologically active compounds from plant tissues for analytical purposes, due to the limited use of orga...

    Sefater Gbashi, Patrick Njobeh, Paul Steenkamp, Hlanganani Tutu and Ntakadzeni Madala

    Chemistry Central Journal 2016 10:37

    Published on: 8 June 2016

  2. Research article

    Determination of adapalene in gel formulation by conventional and derivative synchronous fluorimetric approaches. Application to stability studies and in vitro diffusion test

    Adapalene is a retinoid analogue with actions similar to those of tretinoin. It is used in topical treatment of mild to moderate acne. A survey of the literature reveals that no spectrofluorimetric method has ...

    M. M. Tolba and R. M. El-Gamal

    Chemistry Central Journal 2016 10:33

    Published on: 28 May 2016

  3. Research article

    Analysis of steroid hormones and their conjugated forms in water and urine by on-line solid-phase extraction coupled to liquid chromatography tandem mass spectrometry

    In recent years, endocrine disrupting compounds (EDCs) have been found in rivers that receive significant inputs of wastewater. Among EDCs, natural and synthetic steroid hormones are recognized for their poten...

    A. C. Naldi, P. B. Fayad, M. Prévost and S. Sauvé

    Chemistry Central Journal 2016 10:30

    Published on: 6 May 2016

  4. Research article

    The octanol/water distribution coefficients of ardipusilloside-I and its metabolites, and their permeation characteristics across Caco-2 cell monolayer

    Ardipusilloside-I (ADS-I) is a triterpenoid saponin extracted from Chinese medicinal herb Ardisiapusill A. DC. Previous studies have demonstrated the potent anti-tumor activities of ADS-I both in vitro and in viv...

    Wei-yu Cao, Bin Feng, Li-fei Cheng, Ying Wang, Ji Wang and Xiao-juan Wang

    Chemistry Central Journal 2016 10:29

    Published on: 5 May 2016

  5. Research article

    Simultaneous determination of rhamnose, xylitol, arabitol, fructose, glucose, inositol, sucrose, maltose in jujube (Zizyphus jujube Mill.) extract: comparison of HPLC–ELSD, LC–ESI–MS/MS and GC–MS

    Jujube extract is commonly used as a food additive and flavoring. The sensory properties of the extract, especially sweetness, are a critical factor determining the product quality and therefore affecting cons...

    Shihao Sun, Hui Wang, Jianping Xie and Yue Su

    Chemistry Central Journal 2016 10:25

    Published on: 30 April 2016

  6. Research article

    Disposable screen printed sensor for the electrochemical detection of methamphetamine in undiluted saliva

    Methamphetamine has an adverse effect on the ability to drive safely. Police need to quickly screen potentially impaired drivers therefore a rapid disposable test for methamphetamine is highly desirable. This ...

    Carrie-Ann Bartlett, Sarah Taylor, Carlos Fernandez, Ceri Wanklyn, Daniel Burton, Emma Enston, Aleksandra Raniczkowska, Murdo Black and Lindy Murphy

    Chemistry Central Journal 2016 10:3

    Published on: 1 February 2016

  7. Research article

    Tyrosinase inhibitory activity of flavonoids from Artocarpus heterophyllous

    Tyrosinase is an oxidoreductase that is very important in medicine and cosmetics because the excessive production of melanin causes hyperpigmentation. The development of novel, effective tyrosinase inhibitors...

    Hai Xuan Nguyen, Nhan Trung Nguyen, Mai Ha Khoa Nguyen, Tho Huu Le, Truong Nhat Van Do, Tran Manh Hung and Mai Thanh Thi Nguyen

    Chemistry Central Journal 2016 10:2

    Published on: 29 January 2016

  8. Research article

    Disposable screen printed sensor for the electrochemical detection of delta-9-tetrahydrocannabinol in undiluted saliva

    Cannabis has an adverse effect on the ability to drive safely, therefore a rapid disposable test for Δ9-tetrahydrocannabinol (Δ9-THC), the psychoactive component of cannabis, is highly desirable for roadside test...

    Ceri Wanklyn, Dan Burton, Emma Enston, Carrie-Ann Bartlett, Sarah Taylor, Aleksandra Raniczkowska, Murdo Black and Lindy Murphy

    Chemistry Central Journal 2016 10:1

    Published on: 21 January 2016

  9. Research article

    The acrylamide content of smokeless tobacco products

    There is considerable interest from a regulatory and public health perspective in harmful and potentially harmful constituents in tobacco products, including smokeless tobacco products (STPs). A wide range of ...

    Kevin McAdam, Harriet Kimpton, Carl Vas, David Rushforth, Andrew Porter and Brad Rodu

    Chemistry Central Journal 2015 9:56

    Published on: 12 October 2015

  10. Research article

    A mechanophysical phase transition provides a dramatic example of colour polymorphism: the tribochromism of a substituted tri(methylene)tetrahydrofuran-2-one

    Derivatives of fulgides have been shown to have interesting photochromic properties. We have synthesised a number of such derivatives and have found, in some cases, that crystals can be made to change colour o...

    Abdullah M Asiri, Harry G Heller, David S Hughes, Michael B Hursthouse, John Kendrick, Frank JJ Leusen and Riccardo Montis

    Chemistry Central Journal 2014 8:70

    Published on: 16 December 2014

  11. Research article

    Hair-based rapid analyses for multiple drugs in forensics and doping: application of dynamic multiple reaction monitoring with LC-MS/MS

    Considerable efforts are being extended to develop more effective methods to detect drugs in forensic science for applications such as preventing doping in sport. The aim of this study was to develop a sensiti...

    Iltaf Shah, Andrea Petroczi, Martina Uvacsek, Márta Ránky and Declan P Naughton

    Chemistry Central Journal 2014 8:73

    Published on: 13 December 2014

  12. Research article

    LC–MS/MS determination and pharmacokinetic study of columbianadin in rat plasma after intravenous administration of pure columbianadin

    Columbianadin, one of the active coumarins, is isolated from Radix Angelicae pubescentis which has been used as a traditional Chinese medicine for the treatment of rheumatic diseases for thousands of years. A fas...

    Yan-xu Chang, Chun-peng Wang, Jin Li, Yang Bai, Qian Luo, Jun He, Bing Lu, Tao Wang, Bo-li Zhang and Xiu-mei Gao

    Chemistry Central Journal 2014 8:64

    Published on: 21 November 2014

  13. Research article

    Comparison of binder compositions in Pompeian wall painting styles from Insula Occidentalis

    Although the pigment composition of Pompeian wall paintings has been the object of several studies, a comprehensive characterization of paint binder components is still lacking. This work aimed investigated at...

    Monica Gelzo, Mario Grimaldi, Alessandro Vergara, Valeria Severino, Angela Chambery, Antonio Dello Russo, Ciro Piccioli, Gaetano Corso and Paolo Arcari

    Chemistry Central Journal 2014 8:65

    Published on: 20 November 2014

  14. Research article

    Characterization of the Vitrocell® 24/48 in vitroaerosol exposure system using mainstream cigarette smoke

    Only a few exposure systems are presently available that enable cigarette smoke exposure of living cells at the air-liquid interface, of which one of the most versatile is the Vitrocell® system (Vitrocell® Sys...

    Shoaib Majeed, Stefan Frentzel, Sandra Wagner, Diana Kuehn, Patrice Leroy, Philippe A Guy, Arno Knorr, Julia Hoeng and Manuel C Peitsch

    Chemistry Central Journal 2014 8:62

    Published on: 12 November 2014

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