Analytical Chemistry

This section publishes articles in all areas of analytical chemistry including spectroscopy, crystallography, chromatography, imaging, chemometrics, data processing, and electrochemistry.

Section Editors: Yitao Long, Richard Brereton and Elizabeth Ostler


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  1. Research article

    Investigating and characterizing the binding activity of the immobilized calmodulin to calmodulin-dependent protein kinase I binding domain with atomic force microscopy

    Protein–protein interactions are responsible for many biological processes, and the study of how proteins undergo a conformational change induced by other proteins in the immobilized state can help us to under...

    Xiaoning Zhang and Hongmei Hu

    Chemistry Central Journal 2017 11:128

    Published on: 6 December 2017

  2. Research Article

    Development of new analytical methods for the determination of caffeine content in aqueous solution of green coffee beans

    This study was conducted to develop fast and cost effective methods for the determination of caffeine in green coffee beans. In the present work direct determination of caffeine in aqueous solution of green co...

    Blen Weldegebreal, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Chemistry Central Journal 2017 11:126

    Published on: 5 December 2017

  3. Research article

    Simultaneous determination of brazilin and protosappanin B in Caesalpinia sappan by ionic-liquid dispersive liquid-phase microextraction method combined with HPLC

    The conditions of heating, ionic liquid-based ultrasonic-assisted extraction combined with reverse-phase high performance liquid chromatography were optimized to simultaneously isolate and determinate brazilin...

    Zhaoyang Xia, Dongdong Li, Qing Li, Yan Zhang and Wenyi Kang

    Chemistry Central Journal 2017 11:114

    Published on: 13 November 2017

  4. Research article

    Preparative HPLC for large scale isolation, and salting-out assisted liquid–liquid extraction based method for HPLC–DAD determination of khat (Catha edulis Forsk) alkaloids

    Khat (Catha edulis Forsk) is an evergreen shrub of the Celastraceae family. It is widely cultivated in Yemen and East Africa, where its fresh leaves are habitually chewed for their momentary pleasures and stimula...

    Minaleshewa Atlabachew, Bhagwan Singh Chandravanshi and Mesfin Redi-Abshiro

    Chemistry Central Journal 2017 11:107

    Published on: 17 October 2017

  5. Research article

    Steam distillation/drop-by-drop extraction with gas chromatography–mass spectrometry for fast determination of volatile components in jujube (Ziziphus jujuba Mill.) extract

    Jujube extract is commonly used as a food additive and flavoring. The unique jujube aroma and the mild sweet aroma of the extract are critical factors that determine product quality and affect consumer accepta...

    Shi-Hao Sun, Guo-Bi Chai, Peng Li, Jian-Ping Xie and Yue Su

    Chemistry Central Journal 2017 11:101

    Published on: 13 October 2017

  6. Research article

    Simultaneous determination of cetirizine, phenyl propanolamine and nimesulide using third derivative spectrophotometry and high performance liquid chromatography in pharmaceutical preparations

    The combination between cetirizine (CET), phenylpropanolamine (PPA) and nimesulide (NMS) under trade name Nemeriv Cp tablet is prescribed for nasal congestion, cold, sneezing, and allergy. Among all published ...

    Fatma Ahmed Aly, Nahed EL-Enany, Heba Elmansi and Amany Nabil

    Chemistry Central Journal 2017 11:99

    Published on: 5 October 2017

  7. Research article

    Comparison of various techniques for the extraction of umbelliferone and herniarin in Matricaria chamomilla processing fractions

    Chamomile, a well-known medicinal plant, is a rich source of bioactive compounds, among which two coumarin derivatives, umbelliferone and herniarin, are often found in its extracts. Chamomile extracts have fou...

    Maja Molnar, Nikolina Mendešević, Drago Šubarić, Ines Banjari and Stela Jokić

    Chemistry Central Journal 2017 11:78

    Published on: 5 August 2017

  8. Research article

    Using crystallography, topology and graph set analysis for the description of the hydrogen bond network of triamterene: a rational approach to solid form selection

    This study has demonstrated the use of crystallography, topology and graph set analysis in the description and classification of the complex hydrogen bonded network of triamterene. The aim is to give a brief o...

    David S. Hughes, Amit Delori, Abida Rehman and William Jones

    Chemistry Central Journal 2017 11:63

    Published on: 13 July 2017

  9. Review

    Selective synthesis of Fe3O4Au x Ag y nanomaterials and their potential applications in catalysis and nanomedicine

    In these recent years, magnetite (Fe3O4) has witnessed a growing interest in the scientific community as a potential material in various fields of application namely in catalysis, biosensing, hyperthermia treatme...

    Essy Kouadio Fodjo, Koffi Mouroufié Gabriel, Brou Yapi Serge, Dan Li, Cong Kong and Albert Trokourey

    Chemistry Central Journal 2017 11:58

    Published on: 24 June 2017

  10. Research article

    Effects of temperature, time, and solvent ratio on the extraction of phenolic compounds and the anti-radical activity of Clinacanthus nutans Lindau leaves by response surface methodology

    Clinacanthus nutans Lindau is a well-known plant, native to tropical Asian countries. Reports on this plant that is rich in phenolic compounds have focused on its therapeutic anti-infl...

    Intan Soraya Che Sulaiman, Mahiran Basri, Hamid Reza Fard Masoumi, Wei Jian Chee, Siti Efliza Ashari and Maznah Ismail

    Chemistry Central Journal 2017 11:54

    Published on: 14 June 2017

  11. Research article

    Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation

    Vandetanib (VNT) is a new oral tyrosine kinase inhibitor that acts mainly by inhibiting vascular endothelial growth factor receptor (VEGFR). Fast, specific, sensitive and validated LC–MS/MS was established for...

    Sawsan M. Amer, Adnan A. Kadi, Hany W. Darwish and Mohamed W. Attwa

    Chemistry Central Journal 2017 11:45

    Published on: 30 May 2017

  12. Research article

    Different applications of isosbestic points, normalized spectra and dual wavelength as powerful tools for resolution of multicomponent mixtures with severely overlapping spectra

    Analysis of complex mixture containing three or more components represented a challenge for analysts. New smart spectrophotometric methods have been recently evolved with no limitation. A study of different no...

    Ekram H. Mohamed, Hayam M. Lotfy, Maha A. Hegazy and Shereen Mowaka

    Chemistry Central Journal 2017 11:43

    Published on: 25 May 2017

  13. Research article

    Rapid simultaneous determination of indacaterol maleate and glycopyrronium bromide in inhaler capsules using a validated stability-indicating monolithic LC method

    Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. A combination of indacaterol maleate with glycopyrronium bromide has recently been approved as a once-daily m...

    Sahar Zayed and Fathalla Belal

    Chemistry Central Journal 2017 11:36

    Published on: 4 May 2017

  14. Research article

    Natural product based composite for extraction of arsenic (III) from waste water

    Natural based composites of hydroxyapatite/Gum Arabic designed for removal of toxic metal arsenic (III) from waste water were synthesized and evaluated. Several composites with various compositions were prepar...

    N. Akartasse, E. Mejdoubi, B. Razzouki, K. Azzaoui, S. Jodeh, O. Hamed, M. Ramdani, A. Lamhamdi, M. Berrabah, I. Lahmass, W. Jodeh and S. El Hajjaji

    Chemistry Central Journal 2017 11:33

    Published on: 12 April 2017

  15. Research article

    Non-destructive determination of ethanol levels in fermented alcoholic beverages using Fourier transform mid-infrared spectroscopy

    Traditional fermented alcoholic beverages are indigenous to a particular area and are prepared by the local people using an age-old techniques and locally available raw materials. The main objective of this wo...

    Ayalew Debebe, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Chemistry Central Journal 2017 11:27

    Published on: 24 March 2017

  16. Research article

    Optimization of microwave-assisted extraction of zerumbone from Zingiber zerumbet L. rhizome and evaluation of antiproliferative activity of optimized extracts

    The extraction of bioactive compounds from herbal materials requires optimization in order to recover the highest active dose. Response surface methodology was used to optimize variables affecting the microwav...

    Ali Ghasemzadeh, Hawa Z. E. Jaafar, Asmah Rahmat and Mallappa Kumara Swamy

    Chemistry Central Journal 2017 11:5

    Published on: 5 January 2017

  17. Research article

    Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems

    The diluted aerosols from a cigarette (3R4F) and an e-cigarette (Vype ePen) were compared in two commercially available in vitro exposure systems: the Borgwaldt RM20S and Vitrocell VC10. Dosimetry was assessed...

    Jason Adamson, David Thorne, Benjamin Zainuddin, Andrew Baxter, John McAughey and Marianna Gaça

    Chemistry Central Journal 2016 10:74

    Published on: 9 December 2016

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