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  1. Research article

    2-Benzyl-benzofurans from the tubers of Ophiopogon japonicus

    The overproduction of nitric oxide (NO) is known to involve in various inflammatory processes. A methanol extract of the tubers of Ophiopogon japonicus was found to strongly inhibit NO production. The present pap...

    Nguyen Hai Dang, Nguyen Dinh Chung, Ha Manh Tuan, Nguyen Van Thanh, Nguyen Tuan Hiep, Dongho Lee and Nguyen Tien Dat

    Chemistry Central Journal 2017 11:15

    Published on: 6 February 2017

  2. Research article

    Characterization of major metabolites of polymethoxylated flavonoids in Pericarpium Citri Reticulatae using liver microsomes immobilized on magnetic nanoparticles coupled with UPLC/MS–MS

    The peels of citrus fruits (Pericarpium Citri Reticulatae, PCR) have long been used in traditional Chinese medicines (TCMs). Polymethoxylated flavonoids (PMFs) were found to be the main components present in ...

    Jun Lei, Ying Xue, Yi-Ming Liu and Xun Liao

    Chemistry Central Journal 2017 11:13

    Published on: 6 February 2017

  3. Research article

    The effect of carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-hexyl ester on Peronophythora litchii infection, quality and physiology of postharvest litchi fruits

    Litchi (Litchi chinensis Sonn.) is a subtropical fruit with attractive characteristic of white to creamy semitranslucent flesh and red color in pericap, but it was easily subjected to the infection of Peronophyth...

    Hai Liu, Guoxing Jing, Yueming Jiang, Fuying Luo and Zaifeng Li

    Chemistry Central Journal 2017 11:14

    Published on: 6 February 2017

  4. Research article

    Synthesis and biological evaluation of the new 1,3-dimethylxanthine derivatives with thiazolidine-4-one scaffold

    The xanthine structure has proved to be an important scaffold in the process of developing a wide variety of biologically active molecules such as bronchodilator, hypoglycemiant, anticancer and anti-inflammato...

    Sandra Constantin, Florentina Geanina Lupascu, Maria Apotrosoaei, Ioana Mirela Vasincu, Dan Lupascu, Frederic Buron, Sylvain Routier and Lenuta Profire

    Chemistry Central Journal 2017 11:12

    Published on: 1 February 2017

  5. Research article

    Cheminformatics studies to analyze the therapeutic potential of phytochemicals from Rhazya stricta

    Rhazya stricta is a unique medicinal plant source for many indole alkaloids, non-alkaloids, flavonoids, triterpenes and other unknown molecules with tremendous potential for therapeutic a...

    Abdullah Y. Obaid, Sreedhara Voleti, Roop Singh Bora, Nahid H. Hajrah, Abdulkader M. Shaikh Omer, Jamal S. M. Sabir and Kulvinder Singh Saini

    Chemistry Central Journal 2017 11:11

    Published on: 30 January 2017

  6. Research article

    Thermal degradation of aqueous 2-aminoethylethanolamine in CO2 capture; identification of degradation products, reaction mechanisms and computational studies

    Amine degradation is the main significant problems in amine-based post-combustion CO2 capture, causes foaming, increase in viscosity, corrosion, fouling as well as environmental issues. Therefore it is very impor...

    Idris Mohamed Saeed, Vannajan Sanghiran Lee, Shaukat Ali Mazari, B. Si Ali, Wan Jeffrey Basirun, Anam Asghar, Lubna Ghalib and Badrul Mohamed Jan

    Chemistry Central Journal 2017 11:10

    Published on: 24 January 2017

  7. Review

    Green solvents and technologies for oil extraction from oilseeds

    Oilseeds are crucial for the nutritional security of the global population. The conventional technology used for oil extraction from oilseeds is by solvent extraction. In solvent extraction, n-hexane is used as a...

    S. P. Jeevan Kumar, S. Rajendra Prasad, Rintu Banerjee, Dinesh K. Agarwal, Kalyani S. Kulkarni and K. V. Ramesh

    Chemistry Central Journal 2017 11:9

    Published on: 23 January 2017

  8. Research Article

    Enhanced antibacterial activity of TiO2 nanoparticle surface modified with Garcinia zeylanica extract

    The antibacterial activity of 21 nm TiO2 nanoparticles (NPs) and particles modified with Garcinia zeylanica (G. zeylanica) against Methicillin resistant Staphylococcus aureus was investigated in the presence and ...

    U. L. N. H. Senarathna, S. S. N. Fernando, T. D. C. P. Gunasekara, M. M. Weerasekera, H. G. S. P. Hewageegana, N. D. H. Arachchi, H. D. Siriwardena and P. M. Jayaweera

    Chemistry Central Journal 2017 11:7

    Published on: 12 January 2017

  9. Research article

    Synthesis, spectroscopic, dielectric, molecular docking and DFT studies of (3E)-3-(4-methylbenzylidene)-3,4-dihydro-2H-chromen-2-one: an anticancer agent

    Coumarin (2H-chromen-2-one) and its derivatives have a wide range of biological and pharmaceutical activities. They possess antitumor, anti-HIV, anticoagulant, antimicrobial, antioxidant, and anti-inflammatory ac...

    T. Beena, L. Sudha, A. Nataraj, V. Balachandran, D. Kannan and M. N. Ponnuswamy

    Chemistry Central Journal 2017 11:6

    Published on: 10 January 2017

  10. Research article

    Optimization of microwave-assisted extraction of zerumbone from Zingiber zerumbet L. rhizome and evaluation of antiproliferative activity of optimized extracts

    The extraction of bioactive compounds from herbal materials requires optimization in order to recover the highest active dose. Response surface methodology was used to optimize variables affecting the microwav...

    Ali Ghasemzadeh, Hawa Z. E. Jaafar, Asmah Rahmat and Mallappa Kumara Swamy

    Chemistry Central Journal 2017 11:5

    Published on: 5 January 2017

  11. Research article

    A traditional poly herbal medicine “Le Pana Guliya induces apoptosis in HepG2 and HeLa cells but not in CC1 cells: an in vitro assessment

    “Le Pana Guliya” (LPG) is a polyherbal formulation which is used to treat different types of cancers in traditional medicine. In this study we describe in vitro efficacy and mechanism of action of LPG on two c...

    Nekadage Don Amal Wageesha, Preethi Soysa, Keerthi Atthanayake, Muhammad Iqbal Choudhary and Mahinda Ekanayake

    Chemistry Central Journal 2017 11:2

    Published on: 3 January 2017

  12. Research article

    HPLC estimation of iothalamate to measure glomerular filtration rate in humans

    Glomerular filtration rate (GFR) is usually determined by estimation of iothalamate (IOT) clearance. We have developed and validated an accurate and robust method for the analysis of IOT in human plasma and ur...

    Iltaf Shah, James Barker, Declan P. Naughton, Stephen J. Barton and Syed Salman Ashraf

    Chemistry Central Journal 2016 10:80

    Published on: 12 December 2016

  13. Research article

    In vitro drug release characteristic and cytotoxic activity of silibinin-loaded single walled carbon nanotubes functionalized with biocompatible polymers

    In this paper, we demonstrate the preparation of silibinin-loaded carbon nanotubes (SWSB) with surface coating agents via non-covalent approach as an effective drug delivery system. The resulting surface-coate...

    Julia Meihua Tan, Govindarajan Karthivashan, Shafinaz Abd Gani, Sharida Fakurazi and Mohd Zobir Hussein

    Chemistry Central Journal 2016 10:81

    Published on: 12 December 2016

  14. Research article

    Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems

    The diluted aerosols from a cigarette (3R4F) and an e-cigarette (Vype ePen) were compared in two commercially available in vitro exposure systems: the Borgwaldt RM20S and Vitrocell VC10. Dosimetry was assessed...

    Jason Adamson, David Thorne, Benjamin Zainuddin, Andrew Baxter, John McAughey and Marianna Gaça

    Chemistry Central Journal 2016 10:74

    Published on: 9 December 2016

  15. Research Article

    Design, synthesis, and biological evaluation of the novel glycyrrhetinic acid-cinnamoyl hybrids as anti-tumor agents

    Glycyrrhetinic acid (GA) derivatives had shown not only cytotoxicity but also could trigger apoptosis in various human cancer cell lines. Moreover, cinnamic acid (CA) and its phenolic analogues as potent antit...

    Wenbo Guo, Mengmeng Yan, Bing Xu, Fuhao Chu, Wei Wang, Chenze Zhang, Xiaohui Jia, Yaotian Han, Hongjun Xiang, Yuzhong Zhang, Penglong Wang and Haimin Lei

    Chemistry Central Journal 2016 10:78

    Published on: 1 December 2016

  16. Research Article

    Rapid micellar HPLC analysis of loratadine and its major metabolite desloratadine in nano-concentration range using monolithic column and fluorometric detection: application to pharmaceuticals and biological fluids

    Loratadine is a commonly used selective non-sedating antihistaminic drug. Desloratadine is the active metabolite of loratadine and, in addition, a potential impurity in loratadine bulk powder stated by the Uni...

    Fathalla Belal, Sawsan Abd El-Razeq, Mohamed El-Awady, Sahar Zayed and Sona Barghash

    Chemistry Central Journal 2016 10:79

    Published on: 1 December 2016

  17. Research Article

    Analysis of tilianin and acacetin in Agastache rugosa by high-performance liquid chromatography with ionic liquids-ultrasound based extraction

    Ionic liquid 1-butyl-3-methylimidazolium bromide-methanol-based ultrasonic-assisted extraction (ILUAE) was used to extract tilianin and acacetin from the aerial parts of Agastache rugose (A. rugose), and simultan...

    Jinfeng Wei, Pengran Cao, Jinmei Wang and Wenyi Kang

    Chemistry Central Journal 2016 10:76

    Published on: 29 November 2016

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