Analytical Chemistry

This section publishes peer-reviewed open access articles in all areas of analytical chemistry including spectroscopy, crystallography, chromatography, imaging, chemometrics, data processing, and electrochemistry.

Section Editors: Yitao Long, Richard Brereton and Elizabeth Ostler


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  1. Review

    Selective synthesis of Fe3O4Au x Ag y nanomaterials and their potential applications in catalysis and nanomedicine

    In these recent years, magnetite (Fe3O4) has witnessed a growing interest in the scientific community as a potential material in various fields of application namely in catalysis, biosensing, hyperthermia treatme...

    Essy Kouadio Fodjo, Koffi Mouroufié Gabriel, Brou Yapi Serge, Dan Li, Cong Kong and Albert Trokourey

    Chemistry Central Journal 2017 11:58

    Published on: 24 June 2017

  2. Research article

    Effects of temperature, time, and solvent ratio on the extraction of phenolic compounds and the anti-radical activity of Clinacanthus nutans Lindau leaves by response surface methodology

    Clinacanthus nutans Lindau is a well-known plant, native to tropical Asian countries. Reports on this plant that is rich in phenolic compounds have focused on its therapeutic anti-infl...

    Intan Soraya Che Sulaiman, Mahiran Basri, Hamid Reza Fard Masoumi, Wei Jian Chee, Siti Efliza Ashari and Maznah Ismail

    Chemistry Central Journal 2017 11:54

    Published on: 14 June 2017

  3. Research article

    Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation

    Vandetanib (VNT) is a new oral tyrosine kinase inhibitor that acts mainly by inhibiting vascular endothelial growth factor receptor (VEGFR). Fast, specific, sensitive and validated LC–MS/MS was established for...

    Sawsan M. Amer, Adnan A. Kadi, Hany W. Darwish and Mohamed W. Attwa

    Chemistry Central Journal 2017 11:45

    Published on: 30 May 2017

  4. Research article

    Different applications of isosbestic points, normalized spectra and dual wavelength as powerful tools for resolution of multicomponent mixtures with severely overlapping spectra

    Analysis of complex mixture containing three or more components represented a challenge for analysts. New smart spectrophotometric methods have been recently evolved with no limitation. A study of different no...

    Ekram H. Mohamed, Hayam M. Lotfy, Maha A. Hegazy and Shereen Mowaka

    Chemistry Central Journal 2017 11:43

    Published on: 25 May 2017

  5. Research article

    Rapid simultaneous determination of indacaterol maleate and glycopyrronium bromide in inhaler capsules using a validated stability-indicating monolithic LC method

    Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. A combination of indacaterol maleate with glycopyrronium bromide has recently been approved as a once-daily m...

    Sahar Zayed and Fathalla Belal

    Chemistry Central Journal 2017 11:36

    Published on: 4 May 2017

  6. Research article

    Natural product based composite for extraction of arsenic (III) from waste water

    Natural based composites of hydroxyapatite/Gum Arabic designed for removal of toxic metal arsenic (III) from waste water were synthesized and evaluated. Several composites with various compositions were prepar...

    N. Akartasse, E. Mejdoubi, B. Razzouki, K. Azzaoui, S. Jodeh, O. Hamed, M. Ramdani, A. Lamhamdi, M. Berrabah, I. Lahmass, W. Jodeh and S. El Hajjaji

    Chemistry Central Journal 2017 11:33

    Published on: 12 April 2017

  7. Research article

    Non-destructive determination of ethanol levels in fermented alcoholic beverages using Fourier transform mid-infrared spectroscopy

    Traditional fermented alcoholic beverages are indigenous to a particular area and are prepared by the local people using an age-old techniques and locally available raw materials. The main objective of this wo...

    Ayalew Debebe, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Chemistry Central Journal 2017 11:27

    Published on: 24 March 2017

  8. Research article

    Optimization of microwave-assisted extraction of zerumbone from Zingiber zerumbet L. rhizome and evaluation of antiproliferative activity of optimized extracts

    The extraction of bioactive compounds from herbal materials requires optimization in order to recover the highest active dose. Response surface methodology was used to optimize variables affecting the microwav...

    Ali Ghasemzadeh, Hawa Z. E. Jaafar, Asmah Rahmat and Mallappa Kumara Swamy

    Chemistry Central Journal 2017 11:5

    Published on: 5 January 2017

  9. Research article

    Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems

    The diluted aerosols from a cigarette (3R4F) and an e-cigarette (Vype ePen) were compared in two commercially available in vitro exposure systems: the Borgwaldt RM20S and Vitrocell VC10. Dosimetry was assessed...

    Jason Adamson, David Thorne, Benjamin Zainuddin, Andrew Baxter, John McAughey and Marianna Gaça

    Chemistry Central Journal 2016 10:74

    Published on: 9 December 2016

  10. Research Article

    Rapid micellar HPLC analysis of loratadine and its major metabolite desloratadine in nano-concentration range using monolithic column and fluorometric detection: application to pharmaceuticals and biological fluids

    Loratadine is a commonly used selective non-sedating antihistaminic drug. Desloratadine is the active metabolite of loratadine and, in addition, a potential impurity in loratadine bulk powder stated by the Uni...

    Fathalla Belal, Sawsan Abd El-Razeq, Mohamed El-Awady, Sahar Zayed and Sona Barghash

    Chemistry Central Journal 2016 10:79

    Published on: 1 December 2016

  11. Research Article

    Analysis of tilianin and acacetin in Agastache rugosa by high-performance liquid chromatography with ionic liquids-ultrasound based extraction

    Ionic liquid 1-butyl-3-methylimidazolium bromide-methanol-based ultrasonic-assisted extraction (ILUAE) was used to extract tilianin and acacetin from the aerial parts of Agastache rugose (A. rugose), and simultan...

    Jinfeng Wei, Pengran Cao, Jinmei Wang and Wenyi Kang

    Chemistry Central Journal 2016 10:76

    Published on: 29 November 2016

  12. Research article

    The pharmacokinetics, bioavailability and excretion of bergapten after oral and intravenous administration in rats using high performance liquid chromatography with fluorescence detection

    A sensitive, specific, reproducible and optimized high performance liquid chromatography with fluorescence detection (HPLC-FLD) method for the determination of bergapten in rat plasma was established and appli...

    Xie-an Yu, John Teye Azietaku, Jin Li, Mingrui An, Jun He, Jia Hao, Jun Cao and Yan-xu Chang

    Chemistry Central Journal 2016 10:62

    Published on: 14 October 2016

  13. Research article

    Quantification of plasmid DNA reference materials for Shiga toxin-producing Escherichia coli based on UV, HR-ICP-MS and digital PCR

    The accuracy and metrology traceability of DNA quantification is becoming a critical theme in many fields, including diagnosis, forensic analysis, microorganism detection etc. Thus the research of DNA referenc...

    Wen Liang, Li Xu, Zhiwei Sui, Yan Li, Lanying Li, Yanli Wen, Chunhua Li, Shuzhen Ren and Gang Liu

    Chemistry Central Journal 2016 10:55

    Published on: 12 September 2016

  14. Research article

    Simultaneous quantification of triterpenoic acids by high performance liquid chromatography method in the extracts of gum resin of Boswellia serrata obtained by different extraction techniques

    Boswellia serrata, also known as Indian frankincense is a commercially important medicinal plant which has been used for hundreds of years as an Ayurvedic medicine for the attempted tr...

    Neha Sharma, Vikram Bhardwaj, Samar Singh, Sheikh Abid Ali, D. K. Gupta, Satya Paul, Naresh K. Satti, Suresh Chandra and Mahendra K. Verma

    Chemistry Central Journal 2016 10:49

    Published on: 4 August 2016

  15. Research article

    Tissues-based chemical profiling and semi-quantitative analysis of bioactive components in the root of Salvia miltiorrhiza Bunge by using laser microdissection system combined with UPLC-q-TOF-MS

    The dry root of Salvia miltiorrhiza Bunge (Danshen in Chinese) is an used-widely traditional Chinese herbal medicine with and promising efficacy. This herbal plant has been extensively cultivated in China. Curren...

    Wenjian Xie, Hongjie Zhang, Jianguo Zeng, Hubiao Chen, Zhongzhen Zhao and Zhitao Liang

    Chemistry Central Journal 2016 10:42

    Published on: 13 July 2016

  16. Research article

    The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa

    Pressurized hot water extraction (PHWE) technique has recently gain much attention for the extraction of biologically active compounds from plant tissues for analytical purposes, due to the limited use of orga...

    Sefater Gbashi, Patrick Njobeh, Paul Steenkamp, Hlanganani Tutu and Ntakadzeni Madala

    Chemistry Central Journal 2016 10:37

    Published on: 8 June 2016

  17. Research article

    Determination of adapalene in gel formulation by conventional and derivative synchronous fluorimetric approaches. Application to stability studies and in vitro diffusion test

    Adapalene is a retinoid analogue with actions similar to those of tretinoin. It is used in topical treatment of mild to moderate acne. A survey of the literature reveals that no spectrofluorimetric method has ...

    M. M. Tolba and R. M. El-Gamal

    Chemistry Central Journal 2016 10:33

    Published on: 28 May 2016

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